What is Foundayo pill?
Foundayo is a once-daily oral tablet that contains Orforglipron. It is designed to help you feel fuller sooner, eat less without feeling deprived, and support long-term weight loss alongside sustainable lifestyle changes.
On 10 August 2026, the MHRA made the UK the first country in Europe to authorise Orforglipron for weight management and type 2 diabetes. Foundayo is coming soon to iQ Doctor, and our healthcare professionals will review your health assessment before it can be prescribed.
Register your interest to be among the first to know when consultations open. Full product pricing information will be added once confirmed.
What is Orforglipron?
Orforglipron is the active ingredient of Foundayo, its essentially a GLP-1 receptor agonist. It works by mimicking the action of a naturally occurring hormone, glucagon-like peptide-1 (GLP-1), which your body releases after eating. It acts on the areas of the brain that regulate appetite, helping you feel fuller for longer after meals, have fewer food cravings, and eat less through the day. In people with type 2 diabetes, Orforglipron also helps lower blood sugar levels when they are high.
Orforglipron is not a stimulant. It supports your body's own appetite control, and works best alongside a reduced-calorie diet and increased physical activity.
What makes Foundayo different?
Foundayo offers something new: a once-daily GLP-1pill designed to fit easily into your routine.
Here’s what sets it apart:
What’s similar
- Supports weight loss: Designed to help you feel fuller sooner, eat less without feeling deprived, and support long-term weight loss alongside lifestyle changes
- GLP-1 medication: Works by activating GLP-1 receptors, helping to regulate appetite and food intake
- Dose titration: Your healthcare professional may gradually increase your dose over time to help your body adjust
What’s different
- No injections: Foundayo is taken as a once-daily oral tablet
- Convenient dosing: Designed to be taken once daily without the need for injections
- Small-molecule, non-peptide tablet: Orforglipron is a small-molecule GLP-1 receptor agonist, rather than a peptide-based medicine
Is Foundayo (Orforglipron) the same as Mounjaro?
No, Foundayo and Mounjaro are different medicines, but they are both manufactured by Eli Lilly. Foundayo has the active ingredient Orforglipron which works at GLP-1 receptors whilst Mounjaro (Tirzepatide) is a dual agonist affecting both the GLP-1 and GIP receptors. Mounjaro was the first blockbuster weight loss drug released by Eli Lilly however it was only available as an injection. Foundayo now takes some of the benefits of injectable Mounjaro but comes in the form of an oral tablet.
Why do some people choose Foundayo?
Foundayo gives you the same GLP-1 mechanism as injectable treatments, in tablet form, with some added benefits. There are no needles, pens, or sharps bins to deal with, so if you'd rather not inject, or simply prefer a tablet, Foundayo offers the same class of treatment without the needle. Unlike some other oral GLP-1 tablets, it can also be taken at any time of day, with or without food, so there's no need to wait before eating or drinking afterwards, making it easier to fit around your routine.
The tablets don't need to be kept cold, which makes storage, delivery, and travel simpler, and being small, light, and discreet, there are no cool boxes or sharps to carry through airport security. Altogether, that means one tablet, once a day, fitted around your own schedule rather than the medicine's.
What does the research show?
In the ATTAIN-1 phase 3 trial, which included more than 3,000 adults living with obesity or overweight, people taking the highest dose of orforglipron lost an average of 12.4% of their body weight over 72 weeks, alongside a reduced-calorie diet and increased physical activity. This compares with less than 1% weight loss in the placebo group. Almost 6 in 10 people lost at least 10% of their body weight, and around 4 in 10 lost 15% or more on the highest dose. The trial also showed improvements in markers linked to heart health, including cholesterol, triglycerides, blood pressure, and inflammation.
Results are different for everyone. How much weight you lose can depend on your starting weight, your lifestyle, and how closely you follow your treatment plan.
Who may benefit from Foundayo?
Foundayo may be suitable for adults who meet the criteria for medical weight management. This may include people with a Body Mass Index (BMI) of 30 or above, or a BMI of 27 or above alongside a weight-related health condition such as high blood pressure, high cholesterol, sleep apnoea, heart disease, or type 2 diabetes. A healthcare professional will check whether this treatment is right for you before prescribing it.
How to take Foundayo
Treatment starts on the lowest dose, and increases gradually with a minimum of one month at each level, following this schedule: 0.8mg, 2.5mg, 5.5mg, 9mg, 14.5mg, and 17.2mg. This gradual increase helps your body get used to the medicine and lowers the chance of side effects. Your prescriber will help you decide when to move up to the next dose, do not change your dose without consulting your clinician.
- Take FOUNDAYO orally once daily, with or without food.
- Swallow tablets whole. Do not break, crush, or chew.
- Do not take more than one tablet per day.
Who should not take Foundayo?
This medicine is not suitable for everyone. Do not take Foundayo if you are pregnant, breastfeeding, or trying to become pregnant; if you are under 18 years old; if you have ever had an allergic reaction to Orforglipron or any of its other ingredients; or if you have a personal or family history of a rare thyroid cancer called medullary thyroid cancer, or a condition called MEN 2.
You should also tell your prescriber if you have ever had pancreatitis (swelling of the pancreas), gallbladder problems, type 2 diabetes (especially if you take insulin or other diabetes medicines), diabetic eye disease (retinopathy), kidney problems, or any problems with your stomach or digestion. Your prescriber will use this information to decide if the treatment is safe for you.
The most commonly reported side effects are nausea, constipation, diarrhoea, vomiting, dyspepsia (indigestion), and abdominal pain but these often abate after adjusting to the medication.
Availability
Foundayo is a prescription-only medicine. It is not currently available on the NHS but will be available shortly at IQDoctor. At this stage it is available only through private prescription, following an online consultation and clinical review, in the same way as our other weight management treatments.