What is Difflam Throat & Mouth Spray?
Difflam Throat & Mouth Spray contains benzydamine hydrochloride, a non-steroidal anti-inflammatory medicine (NSAID). It works by relieving pain and reducing inflammation in the mouth and throat.
It can be used for:
- Mouth ulcers
- Sore throat
- Pain in the tongue or gums
- Discomfort from dentures or dental work
Active ingredient Benzydamine hydrochloride
Who is it suitable for?
Suitable for:
- Adults
- Children aged 6 years and over
Not recommended for:
- People allergic to benzydamine or other NSAIDs
- Children under 6 years
- People with severe kidney, liver, or heart problems without medical advice
- Those with mouth infections or open wounds that require medical attention
If symptoms are severe, persistent, or accompanied by fever, seek medical advice.
Who should not use it / Warnings
Do not use if:
- You are allergic to benzydamine or any ingredients
- You have previously reacted to similar anti-inflammatory medicines
Speak to a pharmacist or doctor before use if:
- You are pregnant or breastfeeding
- Symptoms last more than a few days
- You experience worsening pain or swelling
Do not exceed the recommended dose.
How to use
Adults
- 4 to 8 puffs every 1 to 3 hours as needed
Children aged 6 to 12 years
- 4 puffs every 1 to 3 hours
How to apply
- Shake the bottle gently and remove the cap.
- Raise the spray tube into position.
- Aim directly at the sore area in your mouth or throat.
- Spray the required number of puffs.
Avoid swallowing large amounts.
After use
- Wipe the spray tube with a tissue
- Push the spray tube back down after use
- Do not insert objects into the nozzle if blocked
Always follow the instructions on the label.
How to store
- Keep out of the sight and reach of children
- Store below 25°C
- Replace the cap after use
- Do not use after the expiry date
Side effects
Common side effects may include:
- Numbness or tingling in the throat
- Stinging or burning sensation in the mouth
These are usually mild and settle quickly.
Stop using and seek medical help if you develop signs of an allergic reaction such as rash, swelling, or difficulty breathing.
When to seek medical advice
Speak to a healthcare professional if:
- Symptoms last longer than 3 days
- Pain worsens
- You develop fever, rash, or difficulty swallowing
- You experience unusual or severe side effects
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Our Clinical Authors
Written by
Omar El-Gohary
CEO & Superintendent Pharmacist | GPhC Registration: 2059792
Medically reviewed by
Jabbar Ali
MPharm Clinical Lead | GPhC Registration: 2205490
This page has been written by a registered UK pharmacist and reviewed by our clinical team to ensure it is accurate, clear and reflects current clinical guidance.
Last medically reviewed: 20 August 2026
Last updated: 21 August 2026