1. What is the difference between Anusol and Anusol Plus HC?
Anusol Plus HC contains hydrocortisone, which helps reduce inflammation and itching more effectively than standard Anusol products.
What are Anusol Plus HC Suppositories?
Anusol Plus HC Suppositories are used to treat the symptoms of internal piles (haemorrhoids) and inflammation inside the back passage. They are inserted into the rectum, where they melt and release ingredients that soothe irritation, reduce swelling, and relieve discomfort.
These suppositories contain hydrocortisone, a mild steroid that helps reduce inflammation and itching, along with soothing ingredients that protect and calm irritated tissue.
They can help with:
- Internal piles (haemorrhoids)
- Itching, soreness, and irritation in the back passage
- Swelling and inflammation associated with piles
- Discomfort during and after bowel movements
Active ingredients:
- Hydrocortisone — reduces inflammation and itching
- Zinc oxide — helps protect the skin and support healing
- Bismuth compounds — provide soothing and mild antiseptic properties
- Balsam Peru — helps support skin repair
Who are Anusol Plus HC Suppositories suitable for?
This medicine requires a consultation to ensure it is suitable for you.
This medication is suitable for:
- Adults with internal piles or rectal inflammation
This medication is not suitable for:
- Children under 18 years
- Anyone allergic to hydrocortisone or any of the ingredients
- Those with untreated infections in the anal or rectal area
Speak to a pharmacist or doctor before use if:
- You are pregnant or breastfeeding
- Your symptoms include severe pain or bleeding
How to use Anusol Plus HC Suppositories
Use exactly as directed on the label or as advised by your pharmacist.
Typical use:
- Insert one suppository into the back passage in the morning and at night
- You may also use one after each bowel movement if needed
Step-by-step instructions:
- Wash your hands and ensure the area around the back passage is clean and dry
- Remove the suppository from its wrapper
- If necessary, moisten the suppository slightly with water to make insertion easier
- Gently insert the suppository, pointed end first, into the rectum
- Wash your hands after use
Important advice:
- Try to insert the suppository after a bowel movement so it stays in place longer
- The suppository will melt inside the body, this is normal
- Do not use for longer than 7 days unless advised by a doctor
If symptoms do not improve, or if bleeding or pain continues, seek medical advice.
How to store Anusol Plus HC Suppositories
- Store below 25°C
- Keep the suppositories in the original packaging
- Keep out of the sight and reach of children
- Do not use after the expiry date
Like all medicines, this product can cause side effects, although not everyone gets them.
Common side effects can include:
- Mild irritation or burning at the application site
- Temporary itching or discomfort
Stop using and seek medical advice urgently if:
- You develop signs of an allergic reaction such as rash, swelling, or severe irritation
- Symptoms become worse or do not improve
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Frequently Asked Questions
2. How quickly do Anusol Plus HC Suppositories work?
They usually begin relieving irritation and swelling shortly after use, but full relief may take a few days of regular use.
3. Can I use them with other haemorrhoid treatments?
Speak to a pharmacist or doctor before using them with other piles treatments.
4. What should I do if I miss a dose?
Insert the suppository when you remember unless it is almost time for your next dose. Do not use two at the same time.
5. When should I see a doctor about piles?
If symptoms last longer than 7 days, worsen, or if you notice persistent bleeding, seek medical advice.
Our Clinical Authors
This page has been written by a registered UK pharmacist and reviewed by our clinical team to ensure it is accurate, clear and reflects current clinical guidance.
Last medically reviewed: 06 July 2026
Last updated: 06 July 2026