1. How long does Fluconazole take to work?
Many people notice improvement within a few days, but it can take up to 7 days for symptoms to fully clear.
What is Fluconazole 150mg?
Fluconazole is an antifungal medicine used to treat vaginal thrush. It works by stopping the growth of the yeast (fungus) that causes the infection.
It can help relieve symptoms such as:
Fluconazole treats the infection from inside the body with a single capsule.
Active ingredient: Fluconazole 150mg
Who is Fluconazole suitable for?
Fluconazole 150mg is suitable for:
- Adults aged 16 to 60 years with symptoms of vaginal thrush
Do not take and seek advice first if you:
- Are under 16 or over 60 years old
- Are pregnant or breastfeeding
- Are allergic to fluconazole or similar antifungals
- Have liver or kidney problems
- Have heart rhythm issues
- Are taking medicines that may interact with fluconazole
Speak to a doctor or pharmacist if:
- This is your first episode of thrush
- You have frequent episodes (more than 2 in 6 months)
- Your symptoms are unusual or severe
How to take Fluconazole 150mg
Always take Fluconazole as directed in the leaflet or by your pharmacist.
Typical use:
- Take 1 capsule as a single dose
- Swallow whole with water
- Can be taken with or without food
Symptoms usually improve within a few days, but it may take up to 7 days for full relief.
If symptoms do not improve or return quickly, seek medical advice.
How to store Fluconazole
Store the capsule:
- At room temperature
- In the original packaging
- Away from heat and moisture
- Out of the sight and reach of children
Do not use after the expiry date on the pack.
Some people may experience side effects.
Possible side effects include:
- Headache
- Nausea
- Stomach pain
- Diarrhoea
Stop taking the medicine and seek urgent medical help if you develop:
- Signs of an allergic reaction (swelling, rash, difficulty breathing)
- Yellowing of the skin or eyes (liver problems)
- Severe skin reactions
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Frequently Asked Questions
2. Can I take Fluconazole with food?
Yes, it can be taken with or without food.
3. Can I take Fluconazole more than once?
It is usually taken as a single dose. If symptoms return, speak to a doctor or pharmacist before taking another dose.
4. Can I drink alcohol while taking Fluconazole?
Alcohol does not directly affect the medicine, but it may worsen side effects like nausea.
5. Do I still need a cream as well?
Some people use an antifungal cream alongside the capsule to help relieve external symptoms more quickly.
Our Clinical Authors
This page has been written by a registered UK pharmacist and reviewed by our clinical team to ensure it is accurate, clear and reflects current clinical guidance.
Last medically reviewed: 07 July 2026
Last updated: 07 July 2026