1. How quickly does Canesten Combi work?
Symptoms usually improve within a few days, but it may take up to 7 days for full relief.
What is Canesten Combi?
Canesten Combi is a thrush treatment that includes a vaginal pessary and an external cream. It treats the infection internally while also relieving external symptoms such as itching and soreness.
It works by killing the yeast that causes thrush.
It can help with:
- Itching and irritation
- Soreness and redness
- Discomfort during sex or urination
- White discharge
Who is Canesten Combi suitable for?
Canesten Combi is suitable for:
- Adults aged 16 to 60 years with symptoms of thrush
Do not use and seek advice first if you:
- Are allergic to clotrimazole
- Are under 16 or over 60 years old
- Have unusual symptoms such as irregular bleeding or strong-smelling discharge
Speak to a doctor or pharmacist if:
- This is your first episode of thrush
- You have recurrent infections
How to use Canesten Combi
Always use as directed in the leaflet or by your pharmacist.
Typical use
- Insert the pessary into the vagina once at night using the applicator
- Apply the external cream thinly to the affected area 2 to 3 times daily
Continue using the cream until symptoms improve.
Important advice
- Some leakage from the pessary is normal
- Avoid sex during treatment
- Use sanitary pads instead of tampons
How to store Canesten Combi
Store the product:
- Below 25°C
- In the original packaging
- Away from heat and moisture
- Out of the sight and reach of children
Do not use after the expiry date.
Canesten Combi is generally well tolerated.
Possible side effects include:
- Mild burning or irritation
- Itching or redness
Stop using and seek medical advice if you experience:
- Severe irritation
- Signs of an allergic reaction such as swelling or rash
Order Journey
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Frequently Asked Questions
2. Can I use tampons during treatment?
No, tampons can reduce how well the treatment works. Use sanitary pads instead.
3. Can I have sex during treatment?
It is best to avoid sex until treatment is complete.
4. Can I use it during my period?
It is usually best to avoid using the pessary during a heavy period.
5. Does this treatment affect condoms?
Yes, it may damage latex condoms or diaphragms, making them less effective.
Our Clinical Authors
This page has been written by a registered UK pharmacist and reviewed by our clinical team to ensure it is accurate, clear and reflects current clinical guidance.
Last medically reviewed: 07 July 2026
Last updated: 07 July 2026