Why Thousands in the UK Are Switching from Mounjaro to Wegovy
22 August, 2025 | Camran Khan - CTO
Can I Switch From Mounjaro to Wegovy in 2025?
Yes, many people can switch if supply problems or personal choice make Wegovy a better option. There are no official head-to-head trials, so decisions must always be made on an individual basis. A healthcare professional will advise you on when to stop one medication and start the other.
It is usually recommended to have a 7–14 day break (washout period). If side effects were severe, your prescriber may suggest up to four weeks.
Price Comparison: Mounjaro vs Wegovy in 2025
| Wegovy Strength | IQDoctor Wegovy Price (£) | Mounjaro Strength | Mounjaro Prices (£) after Sep 1st |
|---|---|---|---|
| 0.25mg | 129.99 | 2.5mg | 174.99 |
| 0.5mg | 127.99 | 5mg | 194.99 |
| 1.0mg | 127.99 | 7.5mg | 244.99 |
| 1.7mg | 199.99 | 10mg | 274.99 |
| 2.4mg | 241.99 | 12.5mg | 294.99 |
| 7.2mg | Coming soon | 15mg | 304.99 |
Mounjaro is increasing in price by up to 170%, while Wegovy’s price remains stable, making it a more cost-effective option in the UK.
How They Work
- Mounjaro (tirzepatide): Works on both GLP-1 and GIP receptors. May be slightly more effective for weight loss but is newer, more expensive, and may cause more side effects.
- Wegovy (semaglutide): Works only on GLP-1 receptors. It has been used longer, with proven long-term safety, and is approved by NICE in the UK.
How to Switch Safely
1. Consult a Prescriber
Always speak to your GP, obesity specialist, or pharmacy prescriber before changing treatments.
2. Take a Break
Have a 7–14 day break between stopping Mounjaro and starting Wegovy. If side effects were severe, a longer break may be required.
3. Start Wegovy at the Right Dose
Patients can now switch using dose equivalents based on their current Mounjaro strength:
| Mounjaro Dose | Guide for Wegovy Switch |
|---|---|
| 2.5mg | 0.5mg |
| 5mg | 0.5mg |
| 7.5mg | 1mg |
| 10mg | 1mg |
| 12.5mg | 1.7mg |
| 15mg | 2.4mg |
What to Expect
- Week 1–2: Appetite may increase slightly as Mounjaro leaves your system.
- Week 5–12: Appetite suppression should return as Wegovy levels build up.
- Maintenance: Most people settle at 2.4 mg Wegovy per week for long-term weight control.
NHS & NICE Guidance (2025 Update)
Wegovy is now supported for long-term obesity management under NICE guidelines. Treatment usually includes support with:
- Diet and nutrition
- Physical activity
- Behavioural therapy
You can access Wegovy through NHS Tier 3 weight management services or privately.
Final Thoughts
With steep price increases for Mounjaro, Wegovy is becoming a more affordable, clinically safe, and NICE-approved option for weight loss in the UK.
The most important steps when switching are:
- Medical oversight
- A proper washout period
- Using the correct dose guide
Never switch between treatments without consulting a healthcare proffesional.
Reviewed By
Omar El-Gohary
The superintendent and lead pharmacist - registration number 2059792.
Omar is passionate about developing healthcare technology to empower our patients.
