Maximising Weight Loss on Wegovy and Mounjaro

27 February, 2026  |  Holy Winter - Healthcare Writer

Maximising Weight Loss on Wegovy and Mounjaro

Today healthcare professionals at iQ Doctor will look at nutrition improvements and positive changes towards physical activity you should consider adopting alongside the use of GLP-1 medications, such as Wegovy or Mounjaro.

Following a balanced, reduced calorie diet and increasing your physical activity doesn’t only support your overall general wellbeing, such changes also help to support sustainable weight loss and complements GLP-1 weight loss therapy - ideally leading to a healthier body mass index (BMI).

Certain foods and habits naturally stimulate the body’s own production of GLP-1, a naturally occurring hormone, that helps to regulate blood sugar, contributes to slowing down digestion, and, as a result, reduces appetite and overconsumption.

Research shows that a combination of healthy lifestyle changes, balanced nutrition, and utilising GLP-1 medications - such as Wegovy or Mounjaro - can lead to better management of type 2 diabetes and may also help lower the risk of long-term medical conditions such as cardiovascular disease, nerve damage, and kidney issues.

Why Diet and Exercise Matter with GLP-1, Particularly for Weight Loss

The right diet and portion sizes can enhance the effectiveness of GLP-1 weight loss therapy and even support your body’s natural production of said hormones, helping you to achieve better results and sustain the long-term health benefits.

Diet and Weight Loss Tips While Taking GLP-1 Medications

GLP-1 medications help to greatly suppress appetite, and their use ensures meals are smaller in size, whilst also helping the body to feel full for longer. Some examples of more satiating foods that passively contribute to weight loss includes: fibre-rich vegetables, fruits, chicken/turkey/fish, non-processed oats and healthy fats.

When designing your weight loss meal plan, it is important to select foods that will help energy levels stay consistent throughout the day. Some examples of slow-release food include: sweet potato, fruit, and legumes (such as lentils). It is important to avoid processed foods where possible, as they aren't as nutritious and are, often, higher in calories, therefore leading to more eating and undesired weight gaun.

GLP-1 weight loss medications can have uncommon side effects, including constipation. To help minimise this, here are some tips: eat slowly, pay attention to your body’s hunger signals, and drink plenty of water to ensure you stay hydrated.

Foods Not to Eat When Using Weight Loss Medications

To encourage weight loss and ensure glucose levels are consistent, you should reduce the consumption of unhealthy foods such as refined carbohydrates, fried foods, sugary sweets, and fizzy drinks.

Foods That Naturally Support GLP-1 Release

Here are some key foods and nutrients shown to directly encourage GLP-1 optimisation:

1. Protein-Rich Foods

Chicken, turkey, milk, eggs, Greek yoghurt, tofu, lentils, beans and protein supplements have been shown to stimulate GLP-1 secretion and increase fullness.

2. Healthy Fats

Avocados, nuts, seeds, olive oil, oily fish. Fat slows digestion and helps prolong GLP-1 activity, making you feel fuller for longer, meaning that you are less likely to binge eat or consume unnecessarily excess calories outside of the remits of your weight loss meal plan.

3. Fermented Foods & Probiotics

Yoghurt with live cultures, kefir, kimchi, sauerkraut can all contribute to healthy digestive organs. A healthy gut may support GLP-1 production and improve insulin sensitivity.

4. Fibre-Rich Foods

Vegetables, whole grains, legumes, fruits like berries and apples. Soluble fibre slows down digestion, enhances satisfaction after eating, and helps regulate blood sugar.

5. Foods Rich in Omega 3

Oily fish (mackerel, sardines), flaxseeds, chia seeds are all easily accessible foods rich in Omega fatty acids that can be eaten on a weight loss meal plan. Omega-3 fatty acids may help keep your metabolism healthy and improve how GLP-1 works in your body.

Exercise Tips While Taking GLP-1 Medication for Weight Loss

Aim for about 150 minutes of moderate aerobic exercise each week. This could be brisk walking, cycling, swimming, or any activity that raises your heart rate. At a more intermediate level, 10,000 steps a day is often recommended, which equates to roughly 2 hours of walking at a moderate intensity.

Don’t forget strength training! Building and maintaining muscle through weightlifting or bodyweight exercises 2-3 times a week helps boost metabolism and supports weight loss.

Include flexibility and balance exercises like yoga, Pilates, or simple dynamic stretching: these improve flexibility, reduce the risk of injury, and may even alleviate aches and pains you may never have thought you'd be free of!

Important Tips Before You Start Your Weight Loss Journey

Before making any significant lifestyle changes, it's important to talk to your healthcare provider, especially if you have existing health conditions: you may also get in touch with the medical experts at iQ Doctor.

If you have diabetes, it is of vital importance to monitor your blood sugar levels closely, as exercise can directly impact glucose and may require adjustments to your routine.

Additionally, if you experience side effects such as nausea or digestive issues that make eating or staying active difficult, reach out to your GP for tailored advice and support.

iQ Doctor is a registered UK pharmacy that specialises in medical remedies for weight loss (including Wegovy and Mounjaro ), erectile dysfunction , hair loss support and much more. Whether you require over-the-counter relief, or prescription-only medication, the experts at iQ Doctor can assist. Please get in touch if you need any further advice.Starting treatment with iQ Doctor couldn’t be more straightforward, simply set up an appointment with a member of our specialist weight management service team of healthcare professionals and start today.

Also, be sure to keep in touch with iQ Doctor via our social media channels as well as keeping up to date with us by signing up to the mailing list.

This article does not constitute medical advice. Always make sure you make informed decisions in consultation with your healthcare professional.

References:

  1. Cleveland Clinic. (2024). GLP-1 diet: What to eat and what to avoid. Retrieved from https://my.clevelandclinic.org
  2. Diabetes.org. (2023). New GLP-1 therapies enhance quality weight loss by improving muscle health. Retrieved from https://diabetes.org
  3. Drucker, D. J. (2023). Advances in GLP-1 biology and therapy. Diabetes, Obesity & Metabolism, 25(7), 1785–1795.
  4. Health OSU. (2023). Activating GLP-1 naturally through diet and lifestyle. The Ohio State University Wexner Medical Center. Retrieved from https://health.osu.edu
  5. Raun, K., Holst, J. J., & Knop, F. K. (2024). GLP-1 receptor agonists and exercise: Synergistic effects on glucose metabolism and weight loss. Diabetes, Obesity & Metabolism, 26(2), 231–240.
  6. Samms, R. J., & Coghlan, M. P. (2022). Exercise and GLP-1: How physical activity influences incretin hormones. Trends in Endocrinology & Metabolism, 33(5), 349–362.
  7. Sattar, N., Lean, M., & Astrup, A. (2024). Lifestyle and GLP-1 therapy: Integrating pharmacology and behaviour change. The Lancet EClinicalMedicine, 70, 102123.

Reviewed By

Omar El-Gohary

Omar El-Gohary

The superintendent and lead pharmacist - registration number 2059792.

Omar is passionate about developing healthcare technology to empower our patients.

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